Journal of Microbiology and Biotechnology
The Korean Society for Microbiology and Biotechnology publishes the Journal of Microbiology and Biotechnology.

2019 ; Vol.29-7: 1009~1013

AuthorNur Amiera Syuhada Rozman, Woei Yenn Tong, Chean Ring Leong, Wen Nee Tan, Muhammad Ariff Hasanolbasori, Siti Zubaidah Abdullah
Place of dutyUniversiti Kuala Lumpur, Branch Campus Malaysian Institute of Chemical and Engineering Technology, Lot 1988 Kawasan Perindustrian Bandar Vendor, Taboh Naning, 78000 Alor Gajah, Melaka, Malaysia
TitlePotential Antimicrobial Applications of Chitosan Nanoparticles (ChNP)
PublicationInfo J. Microbiol. Biotechnol.2019 ; Vol.29-7
AbstractPolymeric nanoparticles are widely used for drug delivery due to their biodegradability property. Among the wide array of polymers, chitosan has received growing interest among researchers. It was widely used as a vehicle in polymeric nanoparticles for drug targeting. This review explored the current research on the antimicrobial activity of chitosan nanoparticles (ChNP) and the impact on the clinical applications. The antimicrobial activities of ChNP were widely reported against bacteria, fungi, yeasts and algae, in both in vivo and in vitro studies. For pharmaceutical applications, ChNP were used as antimicrobial coating for promoting wound healing, preventing infections and combating the rise of infectious disease. Besides, ChNP also exhibited significant inhibitory on foodborne microorganisms, particularly on fruits and vegetables. It is noteworthy that ChNP can be also applied to deliver antimicrobial drugs, which further enhance the efficiency and stability of the antimicrobial agent. The present review addresses the potential antimicrobial applications of ChNP from these few aspects.
Full-Text
Key_wordChitosan, nanopartile drug delivery, chitosan nanoparticle, microbial infection
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